VACCINATION

There's a lot of
excitement right now around the record
speed vaccines for covid- 19 some of which are
already starting distribution in
parts of the world but given that these
aremRNA vaccines a relatively new technology that has
not been widely used before we wanted to
explain how they work and what happens to
your body from the moment that
needle touches your skin like the
vaccines, we're used to seeing these vaccines
will be injected into the upper muscle
of your arm but unlike
typical vaccines that introduce inactive or weakened forms of a virus will
release genetic material called messenger
RNA so what exactly
does this mean to do well? in a regular cell
of your body, you have DNA inside of the
nucleus and this DNA
stores all the information and instructions
important to the functioning
of your cells your body and
ultimately makes you inside your cell
is machinery that reads through your DNA and transcribes
it into mRNA which then leaves the
nucleus and goes into your cytoplasm and
it's here that the ribosomes in your
cells read the RNA and
depending on the specific code
build a series of amino acids that fold in on
themselves to make proteins that
keep you alive and functioning this process is
known as translation in the fact it's
this the process that
viruses take advantage of in the first
place, they insert their own genetic
information into you and then
your cell machinery unwittingly
starts taking that information and building
proteins to help create more viruses so
back to the needle the mRNA that is
being injected into you from the vaccine also carries genetic
instructions but in this case,
it's only coding for one small part of the virus
instead of the whole the thing you've
probably seen sars cov2 represented like this with the
spikes on it and it's this spike protein
which on its own is harmless that the
vaccine's mRNA codes for the
mRNA makes its way into the cytoplasm of
your cells where the
ribosomes read the information and start to
create the spike proteins once the protein
is made it goes to the cell membrane and
then your cell breaks down and destroys
the injected mRNA instructions
so what good does having a tiny
fragment of the viral spike in your body does
what gives your body and more importantly
your immune system a preview of what the virus
looks like without causing disease
suddenly your antibodies will notice it
and go well this doesn't
belong here which triggers an
immune response to recognize and prepare your body for the real thing without ever having to
come in contact with the actual virus
itself your immune
system essentially gets a head start by
creating powerful antibodies that
can neutralize and kill the real virus
and this antibody memory is stored in your B cells so that if
you are ever infected in the future
with the tsar cov2 virus, your body now has
the upper hand this is known as an
adaptive immune response your body has
already seen these spike proteins before
and therefore it already knows what to do essentially these
mRNA vaccines allow your body to
protect itself from a future infection without ever
having to risk the consequences of
getting the disease covid19 so why haven't
mRNA vaccines have been used before while they are
relatively new researchers have
been experimenting
with them for decades but in the past,
they've been very unstable enzymes in your the body would break down the man quickly
so they needed to be packaged well the ones being
released now have the mRNA encased in
lipid nanoparticles which essentially
protect the mRNA from being degraded since they're
more unstable than other types of vaccines
they have to be kept cold for example
the Pfizer vaccine has to be stored at
minus 70 degrees
celsius and at normal refrigerated
temperatures can only last five days, of course, a global pandemic has certainly
increased the funding and resources going
towards these types of vaccines which
have helped to accelerate their development
what makes these vaccines so
appealing is that unlike
other vaccines they can be made in a lab
with readily available materials and made much
quicker than other types of
vaccines instead of fully developing
non-infectious viruses and then injecting
them these mRNA
vaccines can sort of pass many hurdles by
using your own body in an ingenious way
it's also far more cost-effective to
create mRNA molecules rather than the
proteins themselves and also a lot more
scalable which is helpful when we
are in a global pandemic waiting for a
vaccine so is it safe and
given that it's a relatively new
technology should you be
concerned at all well that's what these
initial trial stages have been for not
only to test whether or not they work
and cause immunity but to make sure
they have minimal side effects as of now
around 70000 people have
been given these vaccines with no
serious concerns a caveat being
that the full research hasn't been
published yet, but it's important to remember that
just because it's safe doesn't mean
there won't be any soreness or pain some
recipients did report aches and pains and as
of now you'll need to
receive two shots to ensure efficacy.
POTENTIAL SIDE
EFFECTS OF COVID VACCINE
Several
coronavirus vaccines have now been approved for use,
either by individual countries, or the EU and
WHO. There are currently more than 50 COVID-19
vaccine candidates in trials. Currently, two
vaccines are authorized and recommended for
COVID-19:
• Pfizer-BioNTech
COVID-19 vaccine
• Moderna’s
COVID-19 vaccine
As of December
28, 2020, large-scale Phase 3 clinical trials
are in progress for three
COVID-19 vaccines
in the United States:
• AstraZeneca’s
COVID-19 vaccine
• Johnsen’s
COVID-19 vaccine
• Novavax’s
COVID-19 vaccine
COVID-19 vaccines
help our bodies develop immunity to the virus that causes COVID-19, without us having
to get the illness. Different types of vaccines
work in different ways to offer protection,
but with all types of vaccines, the body is left
with a supply of “memory” T-lymphocytes,
B-lymphocytes and antibodies that will
remember how to fight that virus in the future. It typically
takes a few weeks for the body to produce
T-lymphocytes and B-lymphocytes after vaccination. Sometimes after
vaccination, the process of building immunity
can cause symptoms, such as fever, muscle
pain, fatigue, etc. These symptoms are
normal and are a sign that the body is building
immunity. So, it’s very
important that you understand the minor
side-effects of Covid vaccine and also we will
discuss some of the rare but serious complications
that can occur.
The most common
side effects that you can experience after
COVID-19 Vaccine includes:
• injection site
pain • tiredness
• headache
• muscle pain
•
chills, swollen lymph nodes
• joint
pain
• fever
• injection site swelling
•
injection site redness and nausea
These are known
as minor or expected side effects of a
vaccine and they can occur not just after the Covid
vaccine but in fact after most of the
vaccines that you receive. These side effects
occur because your body is adapting to the vaccine. Vaccines
work by introducing a small number of
bacteria, viruses, or toxins into the body. Because the
bacteria, virus, or toxin have been killed
or weakened, there's no risk of contracting
the disease in question. However, your body
responds as if it were under attack, and mounts an
immune response. If
in the future, you do
encounter that disease, you'll have an army of
cells and antibodies ready to fight it. This means that
any adverse effects you experience are unlikely to
be caused by bacteria, viruses, or toxins.
Most of the common side effects such as a sore
arm, redness, and fever are caused by the
injection, or by your own immune system fighting
against the weakened invaders.
What are the
chances of serious side effects?
The vaccine can cause
a severe allergic reaction. A severe allergic reaction would usually occur within a few
minutes to one hour after getting a dose of the
COVID-19 Vaccine. For this reason, your vaccination
provider may ask you to stay at the place
where you received your vaccine for monitoring
after vaccination.
Signs of a severe allergic reaction can include:
• Difficulty
breathing
• Swelling of your face and throat
• A fast
heartbeat
• A skin rash all
over your body
• Dizziness and weakness
CAN THE COVID
VACCINE GIVE ME COVID-19?
The simple answer
to this question is a “BIG NO”. None of the
COVID-19 Vaccines contain the SARS-CoV-2 virus,
so it is not possible that you can CONTRACT covid-19 from the covid vaccine.
Labels: covid, side effect, vaccine